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Immunology Research Sponsored by the Dana-Farber Cancer Institute

October 24, 2013

Over the course of her career as a philanthropist, Lois Pope has provided crucial funding for a number of life-saving initiatives. In addition to supporting the Red Cross organization in Israel, financing a clean water system for Guatemalan communities affected by Hurricane Mitch, and making a large donation to the Genocide Response Team, which aims to rescue women and girls in Sudan, Lois Pope sponsors research at the Dana-Farber Cancer Institute. Dana-Farber conducts research in several important cancer research areas, including immunology.

In the field of immunology, Dana-Farber researcher Shannon Turley, PhD, has explored the role of dendritic cells in immunity and tolerance in tumors as well as autoimmune diseases. During her research, Turley discovered an unexpected function of lymph node stromal cells, which play an integral role in the elimination of T cells that react to self-antigen in the intestines. She and her team are continuing to explore the potential of lymph node stroma to benefit patients with tumors or autoimmune disorders. Another researcher at the institute, Glenn Dranoff, MD, is currently making progress in the use of combinatorial vaccines to promote the formation of “killer” T cells over T cells with negative regulatory tendencies, which, if successful, should help patients with cancerous tumors respond more favorably to other cancer treatment methods, such as chemotherapy and radiation.

To learn more about the immunology research performed at the Dana-Farber Cancer Institute, visit www.dana-farber.org.

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From → Philanthropy

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